Publications

Below is the list of scientific publications co-authored by our team members.

2024

Cubillos, P., Ditzer, N., Kolodziejczyk, A., Schwenk, G., Hoffmann, J., Schütze, T. M., Derihaci, R. P., Birdir, C., Köllner, J. E., Petzold, A., Sarov, M., Martin, U., Long, K. R., Wimberger, P., & Albert, M. (2024). The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex. The EMBO Journal, 43(8), 1388–1419. https://doi.org/10.1038/S44318-024-00068-7

Zocher, S., McCloskey, A., Karasinsky, A., Schulte, R., Friedrich, U., Lesche, M., Rund, N., Gage, F. H., Hetzer, M. W., & Toda, T. (2024). Lifelong persistence of nuclear RNAs in the mouse brain. Science, 384(6691), 53–59. https://doi.org/10.1126/science.adf3481

Jarc, L., Bandral, M., Zanfrini, E., Lesche, M., Kufrin, V., Sendra, R., Pezzolla, D., Giannios, I., Khattak, S., Neumann, K., Ludwig, B., & Gavalas, A. (2024). Regulation of multiple signaling pathways promotes the consistent expansion of human pancreatic progenitors in defined conditions. ELife, 13. https://doi.org/10.7554/eLife.89962

Cudak, N., López-Delgado, A. C., Rost, F., Kurth, T., Lesche, M., Reinhardt, S., Dahl, A., Rulands, S., & Knopf, F. (2024). Compartmentalization and synergy of osteoblasts drive bone formation in the regenerating fin. IScience, 27(2). https://doi.org/10.1016/j.isci.2024.108841

Broghammer, F., Korovina, I., Gouda, M., Celotti, M., van Es, J., Lange, I., Brunner, C., Mircetic, J., Coppes, R. P., Gires, O., Dahl, A., Seifert, M., & Cordes, N. (2024). Resistance of HNSCC cell models to pan-FGFR inhibition depends on the EMT phenotype associating with clinical outcome. Molecular Cancer, 23(1). https://doi.org/10.1186/s12943-024-01954-8

Zhang, S., Yun, D., Yang, H., Eckstein, M., Elbait, G. D., Zhou, Y., Lu, Y., Yang, H., Zhang, J., Dörflein, I., Britzen-Laurent, N., Pfeffer, S., Stemmler, M. P., Dahl, A., Mukhopadhyay, D., Chang, D., He, H., Zeng, S., Lan, B., … Pilarsky, C. (2024). Roflumilast inhibits tumor growth and migration in STK11/LKB1 deficient pancreatic cancer. Cell Death Discovery, 10(1). https://doi.org/10.1038/S41420-024-01890-Y

Dinter, L., Karitzky, P. C., Schulz, A., Wurm, A. A., Mehnert, M. C., Sergon, M., Tunger, A., Lesche, M., Wehner, R., Müller, A., Käubler, T., Niessner, H., Dahl, A., Beissert, S., Schmitz, M., Meier, F., Seliger, B., & Westphal, D. (2024). BRAF and MEK inhibitor combinations induce potent molecular and immunological effects in NRAS-mutant melanoma cells: Insights into mode of action and resistance mechanisms. International Journal of Cancer, 154(6), 1057–1072. https://doi.org/10.1002/ijc.34807

Ibneeva, L., Singh, S. P., Sinha, A., Eski, S. E., Wehner, R., Rupp, L., Kovtun, I., Pérez-Valencia, J. A., Gerbaulet, A., Reinhardt, S., Wobus, M., von Bonin, M., Sancho, J., Lund, F., Dahl, A., Schmitz, M., Bornhäuser, M., Chavakis, T., Wielockx, B., & Grinenko, T. (2024). CD38 promotes hematopoietic stem cell dormancy. PLoS Biology, 22(2). https://doi.org/10.1371/JOURNAL.PBIO.3002517

Yi, B., Patrasová, E., Šimůnková, L., Rost, F., Winkler, S., Laubner, A., Reinhardt, S., Dahl, A., & Dalpke, A. H. (2024). Investigating the cause of a 2021 winter wave of COVID-19 in a border region in eastern Germany: a mixed-methods study, August to November 2021. Epidemiology and Infection, 152. https://doi.org/10.1017/S0950268824000761

Rupp, T., Oelschlägel, B., Berjano, R., Mahfoud, H., Buono, D., Wenke, T., Rabitsch, K., Bächli, G., Stanojlovic, V., Cabrele, C., Xiong, W., Knaden, M., Dahl, A., Neinhuis, C., Wanke, S., & Dötterl, S. (2024). Chemical imitation of yeast fermentation by the drosophilid-pollinated deceptive trap-flower Aristolochia baetica (Aristolochiaceae). Phytochemistry, 224. https://doi.org/10.1016/J.PHYTOCHEM.2024.114142

Islam, S., Peart, C., Kehlmaier, C., Sun, Y. H., Lei, F., Dahl, A., Klemroth, S., Alexopoulou, D., del Mar Delgado, M., Laiolo, P., Carlos Illera, J., Dirren, S., Hille, S., Lkhagvasuren, D., Töpfer, T., Kaiser, M., Gebauer, A., Martens, J., Paetzold, C., & Päckert, M. (2024). Museomics help resolving the phylogeny of snowfinches (Aves, Passeridae, Montifringilla and allies). Molecular Phylogenetics and Evolution, 198. https://doi.org/10.1016/J.YMPEV.2024.108135

2023

Osipova, E., Barsacchi, R., Brown, T., Sadanandan, K., Gaede, A. H., Monte, A., Jarrells, J., Moebius, C., Pippel, M., Altshuler, D. L., Winkler, S., Bickle, M., Baldwin, M. W., & Hiller, M. (2023). Loss of a gluconeogenic muscle enzyme contributed to adaptive metabolic traits in hummingbirds. Science (New York, N.Y.), 379(6628), 185–190. https://doi.org/10.1126/SCIENCE.ABN7050

Dressel, N., Natusch, L., Munz, C. M., Ramon, S. C., Morcos, M. N. F., Loff, A., Hiller, B., Haase, C., Schulze, L., Muller, P., Lesche, M., Dahl, A., Luksch, H., Rosen-Wolff, A., Roers, A., Behrendt, R., & Gerbaulet, A. (2023). Activation of the cGAS/STING Axis in Genome-Damaged Hematopoietic Cells Does Not Impact Blood Cell Formation or Leukemogenesis. Cancer Research, 83(17), 2858–2872. https://doi.org/10.1158/0008-5472.CAN-22-3860

Omrani, O., Krepelova, A., Rasa, S. M. M., Syrvinskas, D., Lu, J., Annunziata, F., Garside, G., Bajwa, S., Reinhardt, S., Adam, L., Käppel, S., Ducano, N., Donna, D., Ori, A., Oliviero, S., Rudolph, K. L., & Neri, F. (2023). IFNγ-Stat1 axis drives aging-associated loss of intestinal tissue homeostasis and regeneration. Nature Communications, 14(1), 6109. https://doi.org/10.1038/s41467-023-41683-y

Witt, A., Mateska, I., Palladini, A., Sinha, A., Wölk, M., Harauma, A., Bechmann, N., Pamporaki, C., Dahl, A., Rothe, M., Kopaliani, I., Adolf, C., Riester, A., Wielockx, B., Bornstein, S. R., Kroiss, M., Peitzsch, M., Moriguchi, T., Fedorova, M., … Alexaki, V. I. (2023). Fatty acid desaturase 2 determines the lipidomic landscape and steroidogenic function of the adrenal gland. Science Advances, 9(29). https://doi.org/10.1126/sciadv.adf6710

Shatilovich, A., Gade, V. R., Pippel, M., Hoffmeyer, T. T., Tchesunov, A. V., Stevens, L., Winkler, S., Hughes, G. M., Traikov, S., Hiller, M., Rivkina, E., Schiffer, P. H., Myers, E. W., & Kurzchalia, T. V. (2023). A novel nematode species from the Siberian permafrost shares adaptive mechanisms for cryptobiotic survival with C. elegans dauer larva. PLoS Genetics, 19(7). https://doi.org/10.1371/JOURNAL.PGEN.1010798

Mateska, I., Witt, A., Hagag, E., Sinha, A., Yilmaz, C., Thanou, E., Sun, N., Kolliniati, O., Patschin, M., Abdelmegeed, H., Henneicke, H., Kanczkowski, W., Wielockx, B., Tsatsanis, C., Dahl, A., Walch, A. K., Li, K. W., Peitzsch, M., Chavakis, T., & Alexaki, V. I. (2023). Succinate mediates inflammation-induced adrenocortical dysfunction. ELife, 12. https://doi.org/10.7554/eLife.83064

Bentley, B. P., Carrasco-Valenzuela, T., Ramos, E. K. S., Pawar, H., Arantes, L. S., Alexander, A., Banerjee, S. M., Masterson, P., Kuhlwilm, M., Pippel, M., Mountcastle, J., Haase, B., Uliano-Silva, M., Formenti, G., Howe, K., Chow, W., Tracey, A., Sims, Y., Pelan, S., … Komoroske, L. M. (2023). Divergent sensory and immune gene evolution in sea turtles with contrasting demographic and life histories. Proceedings of the National Academy of Sciences of the United States of America, 120(7). https://doi.org/10.1073/pnas.2201076120

Biswas, U., Mallik, T. D., Pschirer, J., Lesche, M., Sameith, K., & Jessberger, R. (2023). Cohesin SMC1β promotes closed chromatin and controls TERRA expression at spermatocyte telomeres. Life Science Alliance, 6(7). https://doi.org/10.26508/LSA.202201798

2022

Gado, M., Heinrich, A., Wiedersich, D., Sameith, K., Dahl, A., Alexaki, V. I., Swarbrick, M. M., Baschant, U., Grafe, I., Perakakis, N., Bornstein, S. R., Rauner, M., Hofbauer, L. C., & Henneicke, H. (2023). Activation of b-adrenergic receptor signaling prevents glucocorticoid-induced obesity and adipose tissue dysfunction in male mice. American Journal of Physiology – Endocrinology and Metabolism, 324(6), 514–530. https://doi.org/10.1152/ajpendo.00259.2022

Bola, S., Subramanian, P., Calzia, D., Dahl, A., Panfoli, I., Funk, R. H. W., & Roehlecke, C. (2023). Analysis of Electric Field Stimulation in Blue Light Stressed 661W Cells. International Journal of Molecular Sciences, 24(4), 3433. https://doi.org/10.3390/ijms24043433

Sendell-Price, A. T., Tulenko, F. J., Pettersson, M., Kang, D., Montandon, M., Winkler, S., Kulb, K., Naylor, G. P., Phillippy, A., Fedrigo, O., Mountcastle, J., Balacco, J. R., Dutra, A., Dale, R. E., Haase, B., Jarvis, E. D., Myers, G., Burgess, S. M., Currie, P. D., … Schartl, M. (2023). Low mutation rate in epaulette sharks is consistent with a slow rate of evolution in sharks. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-42238-x

Ezhkova, D., Schwarzer, S., Spieß, S., Geffarth, M., Machate, A., Zöller, D., Stucke, J., Alexopoulou, D., Lesche, M., Dahl, A., & Hans, S. (2023). Transcriptome analysis reveals an Atoh1b-dependent gene set downstream of Dlx3b/4b during early inner ear development in zebrafish. Biology Open, 12(6). https://doi.org/10.1242/bio.059911

Burguera, D., Dionigi, F., Kverková, K., Winkler, S., Brown, T., Pippel, M., Zhang, Y., Shafer, M., Nichols, A. L. A., Myers, E., Němec, P., & Musilova, Z. (2023). Expanded olfactory system in ray-finned fishes capable of terrestrial exploration. BMC Biology, 21(1). https://doi.org/10.1186/S12915-023-01661-8

Eckardt, J. N., Stasik, S., Röllig, C., Petzold, A., Sauer, T., Scholl, S., Hochhaus, A., Crysandt, M., Brümmendorf, T. H., Naumann, R., Steffen, B., Kunzmann, V., Einsele, H., Schaich, M., Burchert, A., Neubauer, A., Schäfer-Eckart, K., Schliemann, C., Krause, S. W., … Thiede, C. (2023). Mutated IKZF1 is an independent marker of adverse risk in acute myeloid leukemia. Leukemia, 37(12), 1–9. https://doi.org/10.1038/s41375-023-02061-1

Derks, W., Rode, J., Collin, S., Rost, F., Heinke, P., Hariharan, A., Pickel, L., Simonova, I., Lázár, E., Graham, E., Jashari, R., Andrä, M., Jeppsson, A., Salehpour, M., Alkass, K., Druid, H., Kyriakopoulos, C. P., Taleb, I., Shankar, T. S., … Bergmann, O. (2023). A latent cardiomyocyte regeneration potential in human heart disease. BioRxiv : The Preprint Server for Biology. https://doi.org/10.1101/2023.09.14.557681

Celotto, L., Rost, F., Machate, A., Bläsche, J., Dahl, A., Weber, A., Hans, S., & Brand, M. (2023). Single-cell RNA sequencing unravels the transcriptional network underlying zebrafish retina regeneration. ELife, 12. https://doi.org/10.7554/ELIFE.86507

Hundsdoerfer, A. K., Schell, T., Patzold, F., Wright, C. J., Yoshido, A., Marec, F., Daneck, H., Winkler, S., Greve, C., Podsiadlowski, L., Hiller, M., & Pippel, M. (2023). High-quality haploid genomes corroborate 29 chromosomes and highly conserved synteny of genes in Hyles hawkmoths (Lepidoptera: Sphingidae). BMC Genomics, 24(1). https://doi.org/10.1186/S12864-023-09506-Y

Maier, A. M., Huth, K., Alessandrini, F., Schnautz, B., Arifovic, A., Riols, F., Haid, M., Koegler, A., Sameith, K., Schmidt-Weber, C. B., Esser-von-Bieren, J., & Ohnmacht, C. (2023). The aryl hydrocarbon receptor regulates lipid mediator production in alveolar macrophages. Frontiers in Immunology, 14. https://doi.org/10.3389/fimmu.2023.1157373

Montazid, S., Bandyopadhyay, S., Hart, D. W., Gao, N., Johnson, B., Thrumurthy, S. G., Penn, D. J., Wernisch, B., Bansal, M., Altrock, P. M., Rost, F., Gazinska, P., Ziolkowski, P., Hayee, B. H., Liu, Y., Han, J., Tessitore, A., Koth, J., Bodmer, W. F., … Irshad, S. (2023). Adult stem cell activity in naked mole rats for long-term tissue maintenance. Nature Communications, 14(1). https://doi.org/10.1038/S41467-023-44138-6

Gupta, N., Lindeman, I., Reinhardt, S., Mariotti-Ferrandiz, E., Mujangi-Ebeka, K., Martins-Taylor, K., & Eugster, A. (2022). Single-Cell Analysis and Tracking of Antigen-Specific T Cells: Integrating Paired Chain AIRR-Seq and Transcriptome Sequencing: A Method by the AIRR Community. In Methods in Molecular Biology (Vol. 2453, pp. 379–421). Methods Mol Biol. https://doi.org/10.1007/978-1-0716-2115-8_20

Du, K., Pippel, M., Kneitz, S., Feron, R., da Cruz, I., Winkler, S., Wilde, B., Avila Luna, E. G., Myers, G., Guiguen, Y., Garcia, C. M., & Schartl, M. (2022). Genome biology of the darkedged splitfin, Girardinichthys multiradiatus, and the evolution of sex chromosomes and placentation. Genome Research, 32(3), 583–594. https://doi.org/10.1101/GR.275826.121

Stadtmüller, M., Laubner, A., Rost, F., Winkler, S., Patrasová, E., Šimůnková, L., Reinhardt, S., Beil, J., Dalpke, A. H., & Yi, B. (2022). Emergence and spread of a sub-lineage of SARS-CoV-2 Alpha variant B.1.1.7 in Europe, and with further evolution of spike mutation accumulations shared with the Beta and Gamma variants. Virus Evolution, 8(1). https://doi.org/10.1093/ve/veac010

Nellas, I., Iyer, K. V., Iglesias‐Artola, J. M., Pippel, M., Nadler, A., Eaton, S., & Dye, N. A. (2022). Hedgehog signaling can enhance glycolytic ATP production in the Drosophila wing disc. EMBO Reports. https://doi.org/10.15252/EMBR.202154025

Klapproth, E., Witt, A., Klose, P., Wiedemann, J., Vavilthota, N., Künzel, S. R., Kämmerer, S., Günscht, M., Sprott, D., Lesche, M., Rost, F., Dahl, A., Rauch, E., Kattner, L., Weber, S., Mirtschink, P., Kopaliani, I., Guan, K., Lorenz, K., … El-Armouche, A. (2022). Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction. Nature Communications, 13(1). https://doi.org/10.1038/S41467-022-35331-0

Sanin, D. E., Ge, Y., Marinkovic, E., Kabat, A. M., Castoldi, A., Caputa, G., Grzes, K. M., Curtis, J. D., Thompson, E. A., Willenborg, S., Dichtl, S., Reinhardt, S., Dahl, A., Pearce, E. L., Eming, S. A., Gerbaulet, A., Roers, A., Murray, P. J., & Pearce, E. J. (2022). A common framework of monocyte-derived macrophage activation. Science Immunology, 7(70). https://doi.org/10.1126/SCIIMMUNOL.ABL7482

Taube, F., Georgi, J. A., Kramer, M., Stasik, S., Middeke, J. M., Röllig, C., Krug, U., Krämer, A., Scholl, S., Hochhaus, A., Brümmendorf, T. H., Naumann, R., Petzold, A., Mulet-Lazaro, R., Valk, P. J. M., Steffen, B., Einsele, H., Schaich, M., Burchert, A., … Thiede, C. (2022). CEBPA mutations in 4708 patients with acute myeloid leukemia: differential impact of bZIP and TAD mutations on outcome. Blood, 139(1), 87–103. https://doi.org/10.1182/blood.2020009680

Dichtl, S., Sanin, D. E., Koss, C. K., Willenborg, S., Petzold, A., Tanzer, M. C., Dahl, A., Kabat, A. M., Lindenthal, L., Zeitler, L., Satzinger, S., Strasser, A., Mann, M., Roers, A., Eming, S. A., El Kasmi, K. C., Pearce, E. J., & Murray, P. J. (2022). Gene-selective transcription promotes the inhibition of tissue reparative macrophages by TNF. Life Science Alliance, 5(4), e202101315. https://doi.org/10.26508/lsa.202101315

Yu, Q., Walters, H. E., Pasquini, G., Singh, S. P., León-Periñán, D., Petzold, A., Kesavan, P., Subiran, C., Garteizgogeascoa, I., Knapp, D., Wagner, A., Bernardos, A., Alfonso, M., Nadar, G., Dahl, A., Busskamp, V., Martínez-Máñez, R., & Yun, M. H. (2022). Cellular senescence modulates progenitor cell expansion during axolotl limb regeneration. BioRxiv, 2022.09.01.506196. https://doi.org/10.1016/J.DEVCEL.2023.09.009

Furesi, G., de Jesus Domingues, A. M., Alexopoulou, D., Dahl, A., Hackl, M., Schmidt, J. R., Kalkhof, S., Kurth, T., Taipaleenmäki, H., Conrad, S., Hofbauer, C., Rauner, M., & Hofbauer, L. C. (2022). Exosomal miRNAs from Prostate Cancer Impair Osteoblast Function in Mice. International Journal of Molecular Sciences, 23(3). https://doi.org/10.3390/IJMS23031285

Rosa, A., Giese, W., Meier, K., Alt, S., Klaus-Bergmann, A., Edgar, L. T., Bartels-Klein, E., Collins, R. T., Szymborska, A., Coxam, B., Bernabeu, M. O., & Gerhardt, H. (2022). WASp controls oriented migration of endothelial cells to achieve functional vascular patterning. Development (Cambridge), 149(2). https://doi.org/10.1242/DEV.199853

Roeder, S. S., Burkardt, P., Rost, F., Rode, J., Brusch, L., Coras, R., Englund, E., Håkansson, K., Possnert, G., Salehpour, M., Primetzhofer, D., Csiba, L., Molnár, S., Méhes, G., Tonchev, A. B., Schwab, S., Bergmann, O., & Huttner, H. B. (2022). Evidence for postnatal neurogenesis in the human amygdala. Communications Biology, 5(1). https://doi.org/10.1038/s42003-022-03299-8

Willenborg, S., Roscito, J. G., Gerbaulet, A., Roers, A., Dahl, A., Eming, S. A., & Reinhardt, S. (2022). Isolation of macrophages from mouse skin wounds for single-cell RNA sequencing. STAR Protocols, 3(2), 101337. https://doi.org/10.1016/j.xpro.2022.101337

Eugster, A., Müller, D., Gompf, A., Reinhardt, S., Lindner, A., Ashton, M., Zimmermann, N., Beissert, S., Bonifacio, E., & Günther, C. (2022). A Novel Type I Interferon Primed Dendritic Cell Subpopulation in TREX1 Mutant Chilblain Lupus Patients. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.897500

Zeng, S., Lan, B., Ren, X., Zhang, S., Schreyer, D., Eckstein, M., Yang, H., Britzen-Laurent, N., Dahl, A., Mukhopadhyay, D., Chang, D., Kutschick, I., Pfeffer, S., Bailey, P., Biankin, A., Grützmann, R., & Pilarsky, C. (2022). CDK7 inhibition augments response to multidrug chemotherapy in pancreatic cancer. Journal of Experimental and Clinical Cancer Research, 41(1). https://doi.org/10.1186/s13046-022-02443-w

Kraus, G., Weigelt, M., Reinhardt, S., Petzold, A., Dahl, A., & Bonifacio, E. (2022). Reproducibility of 10x Genomics single cell RNA sequencing method in the immune cell environment. Journal of Immunological Methods, 502, 113227. https://doi.org/10.1016/j.jim.2022.113227

Mitroulis, I., Chrysanthopoulou, A., Divolis, G., Ioannidis, C., Ntinopoulou, M., Tasis, A., Konstantinidis, T., Antoniadou, C., Soteriou, N., Lallas, G., Mitka, S., Lesche, M., Dahl, A., Gembardt, S., Panopoulou, M., Sideras, P., Wielockx, B., Coskun, Ü., Ritis, K., & Skendros, P. (2022). A gene expression map of host immune response in human brucellosis. Frontiers in Immunology, 13. https://doi.org/10.3389/fimmu.2022.951232

Morcos, M. N. F., Li, C., Munz, C. M., Greco, A., Dressel, N., Reinhardt, S., Sameith, K., Dahl, A., Becker, N. B., Roers, A., Höfer, T., & Gerbaulet, A. (2022). Fate mapping of hematopoietic stem cells reveals two pathways of native thrombopoiesis. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-31914-z

Hanna, C. W., Huang, J., Belton, C., Reinhardt, S., Dahl, A., Andrews, S., Francis Stewart, A., Kranz, A., & Kelsey, G. (2022). Loss of histone methyltransferase SETD1B in oogenesis results in the redistribution of genomic histone 3 lysine 4 trimethylation. Nucleic Acids Research, 50(4), 1993–2004. https://doi.org/10.1093/nar/gkac051

Oliveira, C. R., Knapp, D., Elewa, A., Gerber, T., Gonzalez Malagon, S. G., Gates, P. B., Walters, H. E., Petzold, A., Arce, H., Cordoba, R. C., Subramanian, E., Chara, O., Tanaka, E. M., Simon, A., & Yun, M. H. (2022). Tig1 regulates proximo-distal identity during salamander limb regeneration. Nature Communications, 13(1). https://doi.org/10.1038/s41467-022-28755-1

Reinhardt, J., Sharma, V., Stavridou, A., Lindner, A., Reinhardt, S., Petzold, A., Lesche, M., Rost, F., Bonifacio, E., & Eugster, A. (2022). Distinguishing activated T regulatory cell and T conventional cells by single-cell technologies. Immunology, 166(1), 121–137. https://doi.org/10.1111/imm.13460

Houwaart, T., Belhaj, S., Tawalbeh, E., Nagels, D., Fröhlich, Y., Finzer, P., Ciruela, P., Sabrià, A., Herrero, M., Andrés, C., Antón, A., Benmoumene, A., Asskali, D., Haidar, H., von Dahlen, J., Nicolai, J., Stiller, M., Blum, J., Lange, C., … Dilthey, A. T. (2022). Integrated genomic surveillance enables tracing of person-to-person SARS-CoV-2 transmission chains during community transmission and reveals extensive onward transmission of travel-imported infections, Germany, June to July 2021. Euro Surveillance : Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin, 27(43). https://doi.org/10.2807/1560-7917.ES.2022.27.43.2101089

Roscito, J. G., Sameith, K., Kirilenko, B. M., Hecker, N., Winkler, S., Dahl, A., Rodrigues, M. T., & Hiller, M. (2022). Convergent and lineage-specific genomic differences in limb regulatory elements in limbless reptile lineages. 38(3). https://pubmed.ncbi.nlm.nih.gov/35045302/

Wiegleb, G., Reinhardt, S., Dahl, A., & Posnien, N. (2022). Tissue dissociation for single-cell and single-nuclei RNA sequencing for low amounts of input material. Frontiers in Zoology, 19(1). https://doi.org/10.1186/S12983-022-00472-X

Heinke, P., Rost, F., Rode, J., Trus, P., Simonova, I., Lázár, E., Feddema, J., Welsch, T., Alkass, K., Salehpour, M., Zimmermann, A., Seehofer, D., Possnert, G., Damm, G., Druid, H., Brusch, L., & Bergmann, O. (2022). Diploid hepatocytes drive physiological liver renewal in adult humans. Cell Systems, 13(6), 499-507.e12. https://doi.org/10.1016/j.cels.2022.05.001

Singh, S. P., Chawla, P., Hnatiuk, A., Kamel, M., Silva, L. D., Spanjaard, B., Eski, S. E., Janjuha, S., Olivares-Chauvet, P., Kayisoglu, O., Rost, F., Bläsche, J., Kränkel, A., Petzold, A., Kurth, T., Reinhardt, S., Junker, J. P., & Ninov, N. (2022). A single-cell atlas of de novo β-cell regeneration reveals the contribution of hybrid β/δ-cells to diabetes recovery in zebrafish. Development (Cambridge, England), 149(2). https://doi.org/10.1242/dev.199853

2021

Schröpfer, S., Vogt, I., Broggini, G. A. L., Dahl, A., Richter, K., Hanke, M. V., Flachowsky, H., & Peil, A. (2021). Transcriptional profile of AvrRpt2EA-mediated resistance and susceptibility response to Erwinia amylovora in apple. Scientific Reports, 11(1), 8685. https://doi.org/10.1038/s41598-021-88032-x

Suzzi, S., Ahrendt, R., Hans, S., Semenova, S. A., Chekuru, A., Wirsching, P., Kroehne, V., Bilican, S., Sayed, S., Winkler, S., Spieß, S., Machate, A., Kaslin, J., Panula, P., & Brand, M. (2021). Deletion of lrrk2 causes early developmental abnormalities and age-dependent increase of monoamine catabolism in the zebrafish brain. PLoS Genetics, 17(9). https://doi.org/10.1371/JOURNAL.PGEN.1009794

Rhie, A., McCarthy, S. A., Fedrigo, O., Damas, J., Formenti, G., Koren, S., Uliano-Silva, M., Chow, W., Fungtammasan, A., Kim, J., Lee, C., Ko, B. J., Chaisson, M., Gedman, G. L., Cantin, L. J., Thibaud-Nissen, F., Haggerty, L., Bista, I., Smith, M., … Jarvis, E. D. (2021). Towards complete and error-free genome assemblies of all vertebrate species. Nature, 592(7856), 737–746. https://doi.org/10.1038/S41586-021-03451-0

Gerst, F., Kemter, E., Lorza-Gil, E., Kaiser, G., Fritz, A. K., Nano, R., Piemonti, L., Gauder, M., Dahl, A., Nadalin, S., Königsrainer, A., Fend, F., Birkenfeld, A. L., Wagner, R., Heni, M., Stefan, N., Wolf, E., Häring, H. U., & Ullrich, S. (2021). The hepatokine fetuin-A disrupts functional maturation of pancreatic beta cells. Diabetologia, 64(6), 1358–1374. https://doi.org/10.1007/s00125-021-05435-1

Bernal, L., Sotelo-Hitschfeld, P., König, C., Sinica, V., Wyatt, A., Winter, Z., Hein, A., Touska, F., Reinhardt, S., Tragl, A., Kusuda, R., Wartenberg, P., Sclaroff, A., Pfeifer, J. D., Ectors, F., Dahl, A., Freichel, M., Vlachova, V., Brauchi, S., … Zimmermann, K. (2021). Odontoblast TRPC5 channels signal cold pain in teeth. Science Advances, 7(13), eabf5567. https://doi.org/10.1126/sciadv.abf5567

Zocher, S., Overall, R. W., Lesche, M., Dahl, A., & Kempermann, G. (2021). Environmental enrichment preserves a young DNA methylation landscape in the aged mouse hippocampus. Nature Communications, 12(1), 3892. https://doi.org/10.1038/s41467-021-23993-1

Juznić, L., Peuker, K., Strigli, A., Brosch, M., Herrmann, A., Häsler, R., Koch, M., Matthiesen, L., Zeissig, Y., Löscher, B. S., Nuber, A., Schotta, G., Neumeister, V., Chavakis, T., Kurth, T., Lesche, M., Dahl, A., Von Mässenhausen, A., Linkermann, A., … Zeissig, S. (2021). SETDB1 is required for intestinal epithelial differentiation and the prevention of intestinal inflammation. Gut, 70(3), 485–498. https://doi.org/10.1136/gutjnl-2020-321339

Thangapandi, V. R., Knittelfelder, O., Brosch, M., Patsenker, E., Vvedenskaya, O., Buch, S., Hinz, S., Hendricks, A., Nati, M., Herrmann, A., Rekhade, D. R., Berg, T., Matz-Soja, M., Huse, K., Klipp, E., Pauling, J. K., Wodke, J. A., Miranda Ackerman, J., Bonin, M. von, … Subramanian, P. (2021). Loss of hepatic Mboat7 leads to liver fibrosis. Gut, 70(5), 940–950. https://doi.org/10.1136/gutjnl-2020-320853

Goveas, N., Waskow, C., Arndt, K., Heuberger, J., Zhang, Q., Alexopoulou, D., Dahl, A., Birchmeier, W., Anastassiadis, K., Stewart, A. F., & Kranz, A. (2021). MLL1 is required for maintenance of intestinal stem cells. 17(12). https://pubmed.ncbi.nlm.nih.gov/34860830/

Tsata, V., Möllmert, S., Schweitzer, C., Kolb, J., Möckel, C., Böhm, B., Rosso, G., Lange, C., Lesche, M., Hammer, J., Kesavan, G., Beis, D., Guck, J., Brand, M., & Wehner, D. (2021). A switch in pdgfrb+ cell-derived ECM composition prevents inhibitory scarring and promotes axon regeneration in the zebrafish spinal cord. Developmental Cell, 56(4), 509-524.e9. https://doi.org/10.1016/j.devcel.2020.12.009

Al-Fatlawi, A., Malekian, N., García, S., Henschel, A., Kim, I., Dahl, A., Jahnke, B., Bailey, P., Bolz, S. N., Poetsch, A. R., Mahler, S., Grützmann, R., Pilarsky, C., & Schroeder, M. (2021). Deep learning improves pancreatic cancer diagnosis using rna-based variants. Cancers, 13(11). https://doi.org/10.3390/cancers13112654

Muhandes, L., Chapsa, M., Pippel, M., Behrendt, R., Ge, Y., Dahl, A., Yi, B., Dalpke, A., Winkler, S., Hiller, M., Boutin, S., Beissert, S., Jessberger, R., Fallon, P. G., & Roers, A. (2021). Low Threshold for Cutaneous Allergen Sensitization but No Spontaneous Dermatitis or Atopy in FLG-Deficient Mice. Journal of Investigative Dermatology, 141(11), 2611-2619.e2. https://doi.org/10.1016/j.jid.2021.02.763

Aschenbrenner, A. C., Mouktaroudi, M., Krämer, B., Oestreich, M., Antonakos, N., Nuesch-Germano, M., Gkizeli, K., Bonaguro, L., Reusch, N., Baßler, K., Saridaki, M., Knoll, R., Pecht, T., Kapellos, T. S., Doulou, S., Kröger, C., Herbert, M., Holsten, L., Horne, A., … Ulas, T. (2021). Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients. Genome Medicine, 13(1), 7. https://doi.org/10.1186/S13073-020-00823-5

Adusumilli, V. S., Walker, T. L., Overall, R. W., Klatt, G. M., Zeidan, S. A., Zocher, S., Kirova, D. G., Ntitsias, K., Fischer, T. J., Sykes, A. M., Reinhardt, S., Dahl, A., Mansfeld, J., Rünker, A. E., & Kempermann, G. (2021). ROS Dynamics Delineate Functional States of Hippocampal Neural Stem Cells and Link to Their Activity-Dependent Exit from Quiescence. Cell Stem Cell, 28(2), 300-314.e6. https://doi.org/10.1016/j.stem.2020.10.019

Hans, S., Zöller, D., Hammer, J., Stucke, J., Spieß, S., Kesavan, G., Kroehne, V., Eguiguren, J. S., Ezhkova, D., Petzold, A., Dahl, A., & Brand, M. (2021). Cre-Controlled CRISPR mutagenesis provides fast and easy conditional gene inactivation in zebrafish. Nature Communications, 12(1), 1125. https://doi.org/10.1038/s41467-021-21427-6

Wigger, L., Barovic, M., Brunner, A. D., Marzetta, F., Schöniger, E., Mehl, F., Kipke, N., Friedland, D., Burdet, F., Kessler, C., Lesche, M., Thorens, B., Bonifacio, E., Legido-Quigley, C., Barbier Saint Hilaire, P., Delerive, P., Dahl, A., Klose, C., Gerl, M. J., … Solimena, M. (2021). Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories towards type 2 diabetes. Nature Metabolism, 3(7), 1017–1031. https://doi.org/10.1038/s42255-021-00420-9

Yi, B., Poetsch, A. R., Stadtmüller, M., Rost, F., Winkler, S., & Dalpke, A. H. (2021). Phylogenetic analysis of SARS-CoV-2 lineage development across the first and second waves in Eastern Germany in 2020: insights into the cause of the second wave. Epidemiology and Infection, 149. https://doi.org/10.1017/S0950268821001461

Strigli, A., Gopalakrishnan, S., Zeissig, Y., Basic, M., Wang, J., Schwerd, T., Doms, S., Peuker, K., Hartwig, J., Harder, J., Hönscheid, P., Arnold, P., Kurth, T., Rost, F., Petersen, B. S., Forster, M., Franke, A., Kelsen, J. R., Rohlfs, M., … Zeissig, S. (2021). Deficiency in X-linked inhibitor of apoptosis protein promotes susceptibility to microbial triggers of intestinal inflammation. 6(65). https://pubmed.ncbi.nlm.nih.gov/34739342/

Formenti, G., Rhie, A., Balacco, J., Haase, B., Mountcastle, J., Fedrigo, O., Brown, S., Capodiferro, M. R., Al-Ajli, F. O., Ambrosini, R., Houde, P., Koren, S., Oliver, K., Smith, M., Skelton, J., Betteridge, E., Dolucan, J., Corton, C., Bista, I., … Bukhman, Y. (2021). Complete vertebrate mitogenomes reveal widespread repeats and gene duplications. Genome Biology, 22(1). https://doi.org/10.1186/S13059-021-02336-9

Xiong, P., Hulsey, C. D., Fruciano, C., Wong, W. Y., Nater, A., Kautt, A. F., Simakov, O., Pippel, M., Kuraku, S., Meyer, A., & Franchini, P. (2021). The comparative genomic landscape of adaptive radiation in crater lake cichlid fishes. Molecular Ecology, 30(4), 955–972. https://doi.org/10.1111/MEC.15774

Subramanian, P., Gargani, S., Palladini, A., Chatzimike, M., Grzybek, M., Peitzsch, M., Papanastasiou, A. D. D., Pyrina, I., Ntafis, V., Gercken, B., Lesche, M., Petzold, A., Sinha, A., Nati, M., Thangapandi, V. R., Kourtzelis, I., Andreadou, M., Witt, A., Dahl, A., … Chavakis, T. (2021). The RNA binding protein human antigen R is a gatekeeper of liver homeostasis. Hepatology, 75(4), 881–897. https://pubmed.ncbi.nlm.nih.gov/34519101/

Yang, C., Zhou, Y., Marcus, S., Formenti, G., Bergeron, L. A., Song, Z., Bi, X., Bergman, J., Rousselle, M. M. C., Zhou, C., Zhou, L., Deng, Y., Fang, M., Xie, D., Zhu, Y., Tan, S., Mountcastle, J., Haase, B., Balacco, J., … Zhang, G. (2021). Evolutionary and biomedical insights from a marmoset diploid genome assembly. Nature, 594(7862), 227–233. https://doi.org/10.1038/S41586-021-03535-X

2020

Jebb, D., Huang, Z., Pippel, M., Hughes, G. M., Lavrichenko, K., Devanna, P., Winkler, S., Jermiin, L. S., Skirmuntt, E. C., Katzourakis, A., Burkitt-Gray, L., Ray, D. A., Sullivan, K. A. M., Roscito, J. G., Kirilenko, B. M., Dávalos, L. M., Corthals, A. P., Power, M. L., Jones, G., … Teeling, E. C. (2020). Six reference-quality genomes reveal evolution of bat adaptations. Nature, 583(7817), 578–584. https://doi.org/10.1038/s41586-020-2486-3

Morcos, M. N. F., Zerjatke, T., Glauche, I., Munz, C. M., Ge, Y., Petzold, A., Reinhardt, S., Dahl, A., Anstee, N. S., Bogeska, R., Milsom, M. D., Säwén, P., Wan, H., Bryder, D., Roers, A., & Gerbaulet, A. (2020). Continuous mitotic activity of primitive hematopoietic stem cells in adult mice. Journal of Experimental Medicine, 217(6). https://doi.org/10.1084/jem.20191284

de Laval, B., Maurizio, J., Kandalla, P. K., Brisou, G., Simonnet, L., Huber, C., Gimenez, G., Matcovitch-Natan, O., Reinhardt, S., David, E., Mildner, A., Leutz, A., Nadel, B., Bordi, C., Amit, I., Sarrazin, S., & Sieweke, M. H. (2020). C/EBPbeta;-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells. Cell Stem Cell, 26(5), 657-674.e8. https://doi.org/10.1016/j.stem.2020.01.017

Iwaszkiewicz-Grzes, D., Gliwinski, M., Eugster, A., Piotrowska, M., Dahl, A., Marek-Trzonkowska, N., & Trzonkowski, P. (2020). Antigen-reactive regulatory T cells can be expanded in vitro with monocytes and anti-CD28 and anti-CD154 antibodies. Cytotherapy, 22(11), 629–641. https://doi.org/10.1016/j.jcyt.2020.07.001

Kalafati, L., Kourtzelis, I., Schulte-Schrepping, J., Li, X., Hatzioannou, A., Grinenko, T., Hagag, E., Sinha, A., Has, C., Dietz, S., de Jesus Domingues, A. M., Nati, M., Sormendi, S., Neuwirth, A., Chatzigeorgiou, A., Ziogas, A., Lesche, M., Dahl, A., Henry, I., … Chavakis, T. (2020). Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity. Cell, 183(3), 771-785.e12. https://doi.org/10.1016/j.cell.2020.09.058

Stasik, S., Juratli, T. A., Petzold, A., Richter, S., Zolal, A., Schackert, G., Dahl, A., Krex, D., & Thiede, C. (2020). Exome sequencing identifies frequent genomic loss of TET1 in IDH-wild-type glioblastoma. Neoplasia, 22(12). https://doi.org/10.1016/j.neo.2020.10.010

Pippel, M., Jebb, D., Patzold, F., Winkler, S., Vogel, H., Myers, G., Hiller, M., & Hundsdoerfer, A. K. (2020). A highly contiguous genome assembly of the bat hawkmoth Hyles vespertilio (Lepidoptera: Sphingidae). GigaScience, 9(1), 1–10. https://doi.org/10.1093/gigascience/giaa001

Krieg, E., Gupta, K., Dahl, A., Lesche, M., Boye, S., Lederer, A., & Shih, W. M. (2020). A smart polymer for sequence-selective binding, pulldown, and release of DNA targets. Communications Biology, 3(1), 369. https://doi.org/10.1038/s42003-020-1082-2

Ashokkumar, D., Zhang, Q., Much, C., Bledau, A. S., Naumann, R., Alexopoulou, D., Dahl, A., Goveas, N., Fu, J., Anastassiadis, K., Stewart, A. F., & Kranz, A. (2020). MLL4 is required after implantation, whereas MLL3 becomes essential during late gestation. Development, 147(12), dev186999. https://doi.org/10.1242/dev.186999

Lange, C., Rost, F., Machate, A., Reinhardt, S., Lesche, M., Weber, A., Kuscha, V., Dahl, A., Rulands, S., & Brand, M. (2020). Single cell sequencing of radial glia progeny reveals the diversity of newborn neurons in the adult zebrafish brain. Development, 147(1), dev185595. https://doi.org/10.1242/dev.185595

Gillotay, P., Shankar, M., Haerlingen, B., Sema Elif, E., Pozo‐Morales, M., Garteizgogeascoa, I., Reinhardt, S., Kränkel, A., Bläsche, J., Petzold, A., Ninov, N., Kesavan, G., Lange, C., Brand, M., Lefort, A., Libert, F., Detours, V., Costagliola, S., & Sumeet Pal, S. (2020). Single‐cell transcriptome analysis reveals thyrocyte diversity in the zebrafish thyroid gland. EMBO Reports, 21(12). https://doi.org/10.15252/embr.202050612

Mashkaryan, V., Siddiqui, T., Popova, S., Cosacak, M. I., Bhattarai, P., Brandt, K., Govindarajan, N., Petzold, A., Reinhardt, S., Dahl, A., Lefort, R., & Kizil, C. (2020). Type 1 Interleukin-4 Signaling Obliterates Mouse Astroglia in vivo but Not in vitro. Frontiers in Cell and Developmental Biology, 8, 114. https://doi.org/10.3389/fcell.2020.00114

Tsata, V., Kroehne, V., Wehner, D., Rost, F., Lange, C., Hoppe, C., Kurth, T., Reinhardt, S., Petzold, A., Dahl, A., Loeffler, M., Reimer, M. M., & Brand, M. (2020). Reactive oligodendrocyte progenitor cells (re-)myelinate the regenerating zebrafish spinal cord. Development (Cambridge, England), 147(24). https://doi.org/10.1242/dev.193946

Dori, M., Cavalli, D., Lesche, M., Massalini, S., Alieh, L. H. A., de Toledo, B. C., Khudayberdiev, S., Schratt, G., Dahl, A., & Calegari, F. (2020). MicroRNA profiling of mouse cortical progenitors and neurons reveals miR-486-5p as a regulator of neurogenesis. Development, 147(9), dev190520. https://doi.org/10.1242/dev.190520

Adrian-Kalchhauser, I., Blomberg, A., Larsson, T., Musilova, Z., Peart, C. R., Pippel, M., Solbakken, M. H., Suurväli, J., Walser, J. C., Wilson, J. Y., Alm Rosenblad, M., Burguera, D., Gutnik, S., Michiels, N., Töpel, M., Pankov, K., Schloissnig, S., & Winkler, S. (2020). The round goby genome provides insights into mechanisms that may facilitate biological invasions. BMC Biology, 18(1), 11. https://doi.org/10.1186/s12915-019-0731-8

2019

Cosacak, M. I., Bhattarai, P., Reinhardt, S., Petzold, A., Dahl, A., Zhang, Y., & Kizil, C. (2019). Single-Cell Transcriptomics Analyses of Neural Stem Cell Heterogeneity and Contextual Plasticity in a Zebrafish Brain Model of Amyloid Toxicity. Cell Reports, 27(4), 1307-1318.e3. https://doi.org/10.1016/j.celrep.2019.03.090

Steglich, A., Kessel, F., Hickmann, L., Gerlach, M., Lachmann, P., Gembardt, F., Lesche, M., Dahl, A., Federlein, A., Schweda, F., Hugo, C. P. M., & Todorov, V. T. (2019). Renin cells with defective Gsα/cAMP signaling contribute to renal endothelial damage. Pflugers Archiv European Journal of Physiology, 471(9), 1205–1217. https://doi.org/10.1007/s00424-019-02298-9

Mameishvili, E., Serafimidis, I., Iwaszkiewicz, S., Lesche, M., Reinhardt, S., Bölicke, N., Büttner, M., Stellas, D., Papadimitropoulou, A., Szabolcs, M., Anastassiadis, K., Dahl, A., Theis, F., Efstratiadis, A., & Gavalas, A. (2019). Aldh1b1 expression defines progenitor cells in the adult pancreas and is required for Kras-induced pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America, 116(41), 20679–20688. https://doi.org/10.1073/pnas.1901075116

Leonhardt, S., Hoppe, B., Stengel, E., Noll, L., Moll, J., Bässler, C., Dahl, A., Buscot, F., Hofrichter, M., & Kellner, H. (2019). Molecular fungal community and its decomposition activity in sapwood and heartwood of 13 temperate European tree species. PLOS ONE, 14(2), e0212120. https://doi.org/10.1371/journal.pone.0212120

Poser, S. W., Otto, O., Arps-Forker, C., Ge, Y., Herbig, M., Andree, C., Gruetzmann, K., Adasme, M. F., Stodolak, S., Nikolakopoulou, P., Park, D. M., Mcintyre, A., Lesche, M., Dahl, A., Lennig, P., Bornstein, S. R., Schroeck, E., Klink, B., Leker, R. R., … Androutsellis-Theotokis, A. (2019). Controlling distinct signaling states in cultured cancer cells provides a new platform for drug discovery. FASEB Journal, 33(8), 9235–9249. https://doi.org/10.1096/fj.201802603RR

Dori, M., Alieh, L. H. A., Cavalli, D., Massalini, S., Lesche, M., Dahl, A., Calegari, F., Haj Abdullah Alieh, L., Cavalli, D., Massalini, S., Lesche, M., Dahl, A., & Calegari, F. (2019). Sequence and expression levels of circular RNAs in progenitor cell types during mouse corticogenesis. Life Science Alliance, 2(2), e201900354. https://doi.org/10.26508/lsa.201900354

Link-Rachner, C. S., Eugster, A., Rücker-Braun, E., Heidenreich, F., Oelschlägel, U., Dahl, A., Klesse, C., Kuhn, M., Middeke, J. M., Bornhäuser, M., Bonifacio, E., & Schetelig, J. (2019). T-cell receptor-α repertoire of CD8 + T cells following allogeneic stem cell transplantation using next-generation sequencing. Haematologica, 104(3), 622–631. https://doi.org/10.3324/haematol.2018.199802

Tsata, V., Kroehne, V., Reinhardt, S., El-Armouche, A., Brand, M., Wagner, M., & Reimer, M. M. (2019). Electrophysiological properties of adult zebrafish oligodendrocyte progenitor cells. Frontiers in Cellular Neuroscience, 13, 102. https://doi.org/10.3389/fncel.2019.00102

Giannios, I., Serafimidis, I., Anastasiou, V., Pezzolla, D., Lesche, M., Andree, C., Bickle, M., & Gavalas, A. (2019). Protein Methyltransferase Inhibition Decreases Endocrine Specification Through the Upregulation of Aldh1b1 Expression. STEM CELLS, 37(5), 640–651. https://doi.org/10.1002/stem.2979

Müller, S., Glaß, M., Singh, A. K., Haase, J., Bley, N., Fuchs, T., Lederer, M., Dahl, A., Huang, H., Chen, J., Posern, G., & Hüttelmaier, S. (2019). IGF2BP1 promotes SRF-dependent transcription in cancer in a m 6 A- and miRNA-dependent manner. Nucleic Acids Research, 47(1), 375–390. https://doi.org/10.1093/nar/gky1012

Güneş, C., Paszkowski-Rogacz, M., Rahmig, S., Khattak, S., Camgöz, A., Wermke, M., Dahl, A., Bornhäuser, M., Waskow, C., & Buchholz, F. (2019). Comparative RNAi Screens in Isogenic Human Stem Cells Reveal SMARCA4 as a Differential Regulator. Stem Cell Reports, 12(5), 1084–1098. https://doi.org/10.1016/j.stemcr.2019.03.012

Ramasz, B., Krüger, A., Reinhardt, J., Sinha, A., Gerlach, M., Gerbaulet, A., Reinhardt, S., Dahl, A., Chavakis, T., Wielockx, B., & Grinenko, T. (2019). Hematopoietic stem cell response to acute thrombocytopenia requires signaling through distinct receptor tyrosine kinases. Blood, 134(13), 1046–1058. https://doi.org/10.1182/blood.2019000721

Fuchs, Y. F., Sharma, V., Eugster, A., Kraus, G., Morgenstern, R., Dahl, A., Reinhardt, S., Petzold, A., Lindner, A., Löbel, D., & Bonifacio, E. (2019). Gene Expression-Based Identification of Antigen-Responsive CD8+ T Cells on a Single-Cell Level. Frontiers in Immunology, 10, 2568. https://doi.org/10.3389/fimmu.2019.02568

Wiesmueller, F., Kopke, J., Aust, D., Roy, J., Dahl, A., Pilarsky, C., & Grützmann, R. (2019). Silenced ZNF154 is associated with longer survival in resectable pancreatic cancer. International Journal of Molecular Sciences, 20(21), 5437. https://doi.org/10.3390/ijms20215437

Mende, N., Jolly, A., Percin, G. I., Günther, M., Rostovskaya, M., Krishnan, S. M., Oostendorp, R. A. J., Dahl, A., Anastassiadis, K., Höfer, T., & Waskow, C. (2019). Prospective isolation of nonhematopoietic cells of the niche and their differential molecular interactions with HSCs. Blood. https://doi.org/10.1182/blood.2019000176

Rauner, M., Baschant, U., Roetto, A., Pellegrino, R. M., Rother, S., Salbach-Hirsch, J., Weidner, H., Hintze, V., Campbell, G., Petzold, A., Lemaitre, R., Henry, I., Bellido, T., Theurl, I., Altamura, S., Colucci, S., Muckenthaler, M. U., Schett, G., Komla-Ebri, D. S. K., … Hofbauer, L. C. (2019). Transferrin receptor 2 controls bone mass and pathological bone formation via BMP and Wnt signalling. Nature Metabolism, 1(1), 111–124. https://doi.org/10.1038/s42255-018-0005-8

2018

Hendgen, M., Hoppe, B., Döring, J., Friedel, M., Kauer, R., Frisch, M., Dahl, A., & Kellner, H. (2018). Effects of different management regimes on microbial biodiversity in vineyard soils. Scientific Reports, 8(1), 9393. https://doi.org/10.1038/s41598-018-27743-0

Singh, S. P., Janjuha, S., Chaudhuri, S., Reinhardt, S., Kränkel, A., Dietz, S., Eugster, A., Bilgin, H., Korkmaz, S., Zararsız, G., Ninov, N., & Reid, J. E. (2018). Machine learning based classification of cells into chronological stages using single-cell transcriptomics. Scientific Reports, 8(1), 17156. https://doi.org/10.1038/s41598-018-35218-5

Ghouse, S. M., Polikarpova, A., Muhandes, L., Dudeck, J., Tantcheva-Poór, I., Hartmann, K., Lesche, M., Dahl, A., Eming, S., Müller, W., Behrendt, R., & Roers, A. (2018). Although Abundant in Tumor Tissue, Mast Cells Have No Effect on Immunological Micro-milieu or Growth of HPV-Induced or Transplanted Tumors. Cell Reports, 22(1), 27–35. https://doi.org/10.1016/j.celrep.2017.12.010

Roscito, J. G., Sameith, K., Parra, G., Langer, B. E., Petzold, A., Moebius, C., Bickle, M., Rodrigues, M. T., & Hiller, M. (2018). Phenotype loss is associated with widespread divergence of the gene regulatory landscape in evolution. Nature Communications, 9(1), 1–15. https://doi.org/10.1038/s41467-018-07122-z

Moll, J., Kellner, H., Leonhardt, S., Stengel, E., Dahl, A., Bässler, C., Buscot, F., Hofrichter, M., & Hoppe, B. (2018). Bacteria inhabiting deadwood of 13 tree species are heterogeneously distributed between sapwood and heartwood. Environmental Microbiology, 20(10), 3744–3756. https://doi.org/10.1111/1462-2920.14376

Rostovskaya, M., Donsante, S., Sacchetti, B., Alexopoulou, D., Klemroth, S., Dahl, A., Riminucci, M., Bianco, P., & Anastassiadis, K. (2018). Clonal Analysis Delineates Transcriptional Programs of Osteogenic and Adipogenic Lineages of Adult Mouse Skeletal Progenitors. Stem Cell Reports, 11(1), 212–227. https://doi.org/10.1016/j.stemcr.2018.05.014

Vaid, S., Camp, J. G., Hersemann, L., Oegema, C. E., Heninger, A. K., Winkler, S., Brandl, H., Sarov, M., Treutlein, B., Huttner, W. B., & Namba, T. (2018). A novel population of hopx-dependent basal radial glial cells in the developing mouse neocortex. Development (Cambridge), 145(20). https://doi.org/10.1242/dev.169276

Solimena, M., Schulte, A. M., Marselli, L., Ehehalt, F., Richter, D., Kleeberg, M., Mziaut, H., Knoch, K. P., Parnis, J., Bugliani, M., Siddiq, A., Jörns, A., Burdet, F., Liechti, R., Suleiman, M., Margerie, D., Syed, F., Distler, M., Grützmann, R., … Marchetti, P. (2018). Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes. Diabetologia, 61(3), 641–657. https://doi.org/10.1007/s00125-017-4500-3

Brosch, M., Kattler, K., Herrmann, A., von Schönfels, W., Nordström, K., Seehofer, D., Damm, G., Becker, T., Zeissig, S., Nehring, S., Reichel, F., Moser, V., Thangapandi, R. V., Stickel, F., Baretton, G., Röcken, C., Muders, M., Matz-Soja, M., Krawczak, M., … Hampe, J. (2018). Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control. Nature Communications, 9(1), 4150. https://doi.org/10.1038/s41467-018-06611-5

Klapproth, E., Dickreuter, E., Zakrzewski, F., Seifert, M., Petzold, A., Dahl, A., Schröck, E., Klink, B., & Cordes, N. (2018). Whole exome sequencing identifies mTOR and KEAP1 as potential targets for radiosensitization of HNSCC cells refractory to EGFR and β1 integrin inhibition. Oncotarget, 9(26), 18099–18114. https://doi.org/10.18632/oncotarget.24266

Tavano, S., Taverna, E., Kalebic, N., Haffner, C., Namba, T., Dahl, A., Wilsch-Bräuninger, M., Paridaen, J. T. M. L., & Huttner, W. B. (2018). Insm1 Induces Neural Progenitor Delamination in Developing Neocortex via Downregulation of the Adherens Junction Belt-Specific Protein Plekha7. Neuron, 97(6), 1299-1314.e8. https://doi.org/10.1016/j.neuron.2018.01.052

Mitroulis, I., Ruppova, K., Wang, B., Chen, L. S., Grzybek, M., Grinenko, T., Eugster, A., Troullinaki, M., Palladini, A., Kourtzelis, I., Chatzigeorgiou, A., Schlitzer, A., Beyer, M., Joosten, L. A. B., Isermann, B., Lesche, M., Petzold, A., Simons, K., Henry, I., … Chavakis, T. (2018). Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity. Cell, 172(1–2), 147-161.e12. https://doi.org/10.1016/j.cell.2017.11.034

Arndt, K., Kranz, A., Fohgrub, J., Jolly, A., Bledau, A. S., Virgilio, M. Di, Lesche, M., Dahl, A., Höfer, T., Stewart, A. F., & Waskow, C. (2018). SETD1A protects HSCs from activation-induced functional decline in vivo. Blood, 131(12), 1311–1324. https://doi.org/10.1182/blood-2017-09-806844

Singh, R. P., Grinenko, T., Ramasz, B., Franke, K., Lesche, M., Dahl, A., Gassmann, M., Chavakis, T., Henry, I., & Wielockx, B. (2018). Hematopoietic Stem Cells but Not Multipotent Progenitors Drive Erythropoiesis during Chronic Erythroid Stress in EPO Transgenic Mice. Stem Cell Reports, 10(6), 1908–1919. https://doi.org/10.1016/j.stemcr.2018.04.012

Grohme, M. A., Schloissnig, S., Rozanski, A., Pippel, M., Young, G. R., Winkler, S., Brandl, H., Henry, I., Dahl, A., Powell, S., Hiller, M., Myers, E., & Rink, J. C. (2018). The genome of Schmidtea mediterranea and the evolution of core cellular mechanisms. Nature, 554(7690), 56–61. https://doi.org/10.1038/nature25473

Schmidt, K., Zhang, Q., Tasdogan, A., Petzold, A., Dahl, A., Arneth, B. M., Slany, R., Fehling, H. J., Kranz, A., Stewart, A. F., & Anastassiadis, K. (2018). The H3K4 methyltransferase Setd1b is essential for hematopoietic stem and progenitor cell homeostasis in mice. ELife, 7. https://doi.org/10.7554/elife.27157

Papadimitriou, C., Celikkaya, H., Cosacak, M. I., Mashkaryan, V., Bray, L., Bhattarai, P., Brandt, K., Hollak, H., Chen, X., He, S., Antos, C. L., Lin, W., Thomas, A. K., Dahl, A., Kurth, T., Friedrichs, J., Zhang, Y., Freudenberg, U., Werner, C., & Kizil, C. (2018). 3D Culture Method for Alzheimer’s Disease Modeling Reveals Interleukin-4 Rescues Aβ42-Induced Loss of Human Neural Stem Cell Plasticity. Developmental Cell, 46(1), 85-101.e8. https://doi.org/10.1016/j.devcel.2018.06.005

Pfeiffer, F., Zamora-Lagos, M.-A., Blettinger, M., Yeroslaviz, A., Dahl, A., Gruber, S., & Habermann, B. H. (2018). The complete and fully assembled genome sequence of Aeromonas salmonicida subsp. pectinolytica and its comparative analysis with other Aeromonas species: investigation of the mobilome in environmental and pathogenic strains. BMC Genomics, 19(1), 20. https://doi.org/10.1186/s12864-017-4301-6

Tomizawa, S., Kobayashi, Y., Shirakawa, T., Watanabe, K., Mizoguchi, K., Hoshi, I., Nakajima, K., Nakabayashi, J., Singh, S., Dahl, A., Alexopoulou, D., Seki, M., Suzuki, Y., Ne Royo, H., Peters, A. H. F. M., Anastassiadis, K., Stewart, A. F., & Ohbo, K. (2018). Kmt2b conveys monovalent and bivalent H3K4me3 in mouse spermatogonial stem cells at germline and embryonic promoters. Development, 145(23), dev169102. https://doi.org/10.1242/dev.169102

Nowoshilow, S., Schloissnig, S., Fei, J. F., Dahl, A., Pang, A. W. C., Pippel, M., Winkler, S., Hastie, A. R., Young, G., Roscito, J. G., Falcon, F., Knapp, D., Powell, S., Cruz, A., Cao, H., Habermann, B., Hiller, M., Tanaka, E. M., & Myers, E. W. (2018). The axolotl genome and the evolution of key tissue formation regulators. Nature, 554(7690), 50–55. https://doi.org/10.1038/nature25458

Roscito, J. G., Sameith, K., Pippel, M., Francoijs, K.-J., Winkler, S., Dahl, A., Papoutsoglou, G., Myers, G., & Hiller, M. (2018). The genome of the tegu lizard Salvator merianae : combining Illumina, PacBio, and optical mapping data to generate a highly contiguous assembly. GigaScience, 7(12). https://doi.org/10.1093/gigascience/giy141

2017

Albrecht, V., Zweiniger, C., Surendranath, V., Lang, K., Schöfl, G., Dahl, A., Winkler, S., Lange, V., Böhme, I., & Schmidt, A. H. (2017). Dual redundant sequencing strategy: Full-length gene characterisation of 1056 novel and confirmatory HLA alleles. HLA, 90(2), 79–87.

Zhang, W., Fu, J., Liu, J., Wang, H., Schiwon, M., Janz, S., Schaffarczyk, L., von der Goltz, L., Ehrke-Schulz, E., Dörner, J., Solanki, M., Boehme, P., Bergmann, T., Lieber, A., Lauber, C., Dahl, A., Petzold, A., Zhang, Y., Stewart, A. F., & Ehrhardt, A. (2017). An Engineered Virus Library as a Resource for the Spectrum-wide Exploration of Virus and Vector Diversity. Cell Reports, 19(8), 1698–1709. https://doi.org/10.1016/j.celrep.2017.05.008

Kroehne, V., Tsata, V., Marrone, L., Froeb, C., Reinhardt, S., Gompf, A., Dahl, A., Sterneckert, J., & Reimer, M. M. (2017). Primary Spinal OPC Culture System from Adult Zebrafish to Study Oligodendrocyte Differentiation In Vitro. Frontiers in Cellular Neuroscience, 11, 284. https://doi.org/10.3389/fncel.2017.00284

Link, C. S., Hölig, K., Rücker-Braun, E., Lang, K., Kuhn, M., Eugster, A., Klesse, C., Schmiedgen, M., Heidenreich, F., Oelschlägel, U., Dahl, A., Bornhäuser, M., Bonifacio, E., & Schetelig, J. (2017). Assessment of the T cell receptor repertoire in long-term platelet donors by next generation sequencing. British Journal of Haematology. https://doi.org/10.1111/bjh.14576

Fuchs, Y. F., Eugster, A., Dietz, S., Sebelefsky, C., Kühn, D., Wilhelm, C., Lindner, A., Gavrisan, A., Knoop, J., Dahl, A., Ziegler, A.-G., & Bonifacio, E. (2017). CD8+ T cells specific for the islet autoantigen IGRP are restricted in their T cell receptor chain usage. Scientific Reports, 7(November 2016), 44661. https://doi.org/10.1038/srep44661

Arulmozhivarman, G., Kräter, M., Wobus, M., Friedrichs, J., Bejestani, E. P., Müller, K., Lambert, K., Alexopoulou, D., Dahl, A., Stöter, M., Bickle, M., Shayegi, N., Hampe, J., Stölzel, F., Brand, M., von Bonin, M., & Bornhäuser, M. (2017). Zebrafish In-Vivo Screening for Compounds Amplifying Hematopoietic Stem and Progenitor Cells: – Preclinical Validation in Human CD34+ Stem and Progenitor Cells. Scientific Reports, 7(1), 12084. https://doi.org/10.1038/s41598-017-12360-0

Bandoła, J., Richter, C., Ryser, M., Jamal, A., Ashton, M. P., von Bonin, M., Kuhn, M., Dorschner, B., Alexopoulou, D., Navratiel, K., Roeder, I., Dahl, A., Hedrich, C. M., Bonifacio, E., Brenner, S., & Thieme, S. (2017). Neurotrophin Receptor p75NTR Regulates Immune Function of Plasmacytoid Dendritic Cells. Front Immunol, 8, 981.

Cornils, K., Thielecke, L., Winkelmann, D., Aranyossy, T., Lesche, M., Dahl, A., Roeder, I., Fehse, B., & Glauche, I. (2017). Clonal competition in BcrAbl-driven leukemia: how transplantations can accelerate clonal conversion. Mol Cancer, 16(1), 120.

Theil, A., Wilhelm, C., Kuhn, M., Petzold, A., Tuve, S., Oelschlägel, U., Dahl, A., Bornhäuser, M., Bonifacio, E., & Eugster, A. (2017). T cell receptor repertoires after adoptive transfer of expanded allogeneic regulatory T cells. Clin Exp Immunol, 187(2), 316–324.

Brici, D., Zhang, Q., Reinhardt, S., Dahl, A., Hartmann, H., Schmidt, K., Goveas, N., Huang, J., Gahurova, L., Kelsey, G., Anastassiadis, K., Stewart, A. F., & Kranz, A. (2017). Setd1b, encoding a histone 3 lysine 4 methyltransferase, is a maternal effect gene required for the oogenic gene expression program. Development, 144(14), 2606–2617.

Serafimidis, I., Rodriguez-Aznar, E., Lesche, M., Yoshioka, K., Takuwa, Y., Dahl, A., Pan, D., & Gavalas, A. (2017). Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling. PLoS Biology, 15(3). https://doi.org/10.1371/journal.pbio.2000949

Herold, S., Kuhn, M., Bonin, M. v, Stange, T., Platzbecker, U., Radke, J., Lange, T., Sockel, K., Gutsche, K., Schetelig, J., Röllig, C., Schuster, C., Roeder, I., Dahl, A., Mohr, B., Serve, H., Brandts, C., Ehninger, G., Bornhäuser, M., & Thiede, C. (2017). Donor cell leukemia: evidence for multiple preleukemic clones and parallel long term clonal evolution in donor and recipient. Leukemia, 31(7), 1637–1640. https://doi.org/10.1038/leu.2017.104

Akpınar, M., Lesche, M., Fanourgakis, G., Fu, J., Anasstasiadis, K., Dahl, A., Jessberger, R., Anastassiadis, K., Dahl, A., & Jessberger, R. (2017). Correction: TDRD6 mediates early steps of spliceosome maturation in primary spermatocytes. PLoS Genet, 13(3), e1006989.

Thielecke, L., Aranyossy, T., Dahl, A., Tiwari, R., Roeder, I., Geiger, H., Fehse, B., Glauche, I., & Cornils, K. (2017). Limitations and challenges of genetic barcode quantification. Scientific Reports, 7, 43249. https://doi.org/10.1038/srep43249

2016

Fanourgakis, G., Lesche, M., Akpinar, M., Dahl, A., & Jessberger, R. (2016). Chromatoid Body Protein TDRD6 Supports Long 3’ UTR Triggered Nonsense Mediated mRNA Decay. PLoS Genetics, 12(5). https://doi.org/10.1371/journal.pgen.1005857

Peschke, K., Achleitner, M., Frenzel, K., Gerbaulet, A., Ada, S. R., Zeller, N., Lienenklaus, S., Lesche, M., Poulet, C., Naumann, R., Dahl, A., Ravens, U., Günther, C., Müller, W., Knobeloch, K.-P., Prinz, M., Roers, A., & Behrendt, R. (2016). Loss of Trex1 in Dendritic Cells Is Sufficient To Trigger Systemic Autoimmunity. The Journal of Immunology, 197(6), 2157–2166. https://doi.org/10.4049/jimmunol.1600722

Bhattarai, P., Thomas, A. K., Cosacak, M. I., Papadimitriou, C., Mashkaryan, V., Froc, C., Reinhardt, S., Kurth, T., Dahl, A., Zhang, Y., & Kizil, C. (2016). IL4/STAT6 Signaling Activates Neural Stem Cell Proliferation and Neurogenesis upon Amyloid-β42 Aggregation in Adult Zebrafish Brain. Cell Reports, 17(4), 941–948. https://doi.org/10.1016/j.celrep.2016.09.075

de Jesus Domingues, A. M., Artegiani, B., Dahl, A., & Calegari, F. (2016). Identification of Tox chromatin binding properties and downstream targets by DamID-Seq. Genomics Data, 7, 264–268. https://doi.org/10.1016/j.gdata.2016.02.003

Anastasiou, V., Ninou, E., Alexopoulou, D., Stertmann, J., Müller, A., Dahl, A., Solimena, M., Speier, S., Serafimidis, I., & Gavalas, A. (2016). Aldehyde dehydrogenase activity is necessary for beta cell development and functionality in mice. Diabetologia, 59(1), 139–150. https://doi.org/10.1007/s00125-015-3784-4

Link, C. S., Eugster, A., Heidenreich, F., Rücker-Braun, E., Schmiedgen, M., Oelschlägel, U., Kühn, D., Dietz, S., Fuchs, Y., Dahl, A., Domingues, A. M. J., Klesse, C., Schmitz, M., Ehninger, G., Bornhäuser, M., Schetelig, J., & Bonifacio, E. (2016). Abundant cytomegalovirus (CMV) reactive clonotypes in the CD8+ T cell receptor alpha repertoire following allogeneic transplantation. Clinical and Experimental Immunology, 184(3), 389–402. https://doi.org/10.1111/cei.12770

2015

Wermke, M., Camgoz, A., Paszkowski-Rogacz, M., Thieme, S., Von Bonin, M., Dahl, A., Platzbecker, U., Theis, M., Ehninger, G., Brenner, S., Bornhäuser, M., & Buchholz, F. (2015). RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates fasudil as an antileukemic drug. Blood, 125(24), 3760–3768. https://doi.org/10.1182/blood-2014-07-590646

Eugster, A., Lindner, A., Catani, M., Heninger, A.-K., Dahl, A., Klemroth, S., Kühn, D., Dietz, S., Bickle, M., Ziegler, A.-G., & Bonifacio, E. (2015). High Diversity in the TCR Repertoire of GAD65 Autoantigen-Specific Human CD4 ⁺ T Cells. The Journal of Immunology, 194(6), 2531–2538. https://doi.org/10.4049/jimmunol.1403031

Colasante, G., Lignani, G., Rubio, A., Medrihan, L., Yekhlef, L., Sessa, A., Massimino, L., Giannelli, S. G., Sacchetti, S., Caiazzo, M., Leo, D., Alexopoulou, D., Dell’Anno, M. T., Ciabatti, E., Orlando, M., Studer, M., Dahl, A., Gainetdinov, R. R., Taverna, S., … Broccoli, V. (2015). Rapid Conversion of Fibroblasts into Functional Forebrain GABAergic Interneurons by Direct Genetic Reprogramming. Cell Stem Cell. https://doi.org/10.1016/j.stem.2015.09.002

Günther, C., Kind, B., Reijns, M. A. M., Berndt, N., Martinez-Bueno, M., Wolf, C., T??ngler, V., Chara, O., Lee, Y. A., Hübner, N., Bicknell, L., Blum, S., Krug, C., Schmidt, F., Kretschmer, S., Koss, S., Astell, K. R., Ramantani, G., Bauerfeind, A., … Lee-Kirsch, M. A. (2015). Defective removal of ribonucleotides from DNA promotes systemic autoimmunity. Journal of Clinical Investigation, 125(1), 413–424. https://doi.org/10.1172/JCI78001

Artegiani, B., de Jesus Domingues, A. M., Bragado Alonso, S., Brandl, E., Massalini, S., Dahl, A., & Calegari, F. (2015). Tox: a multifunctional transcription factor and novel regulator of mammalian corticogenesis. The EMBO Journal, 34(7), 896–910. https://doi.org/10.15252/embj.201490061

Bonifacio, E., Dietz, S., Bickle, M., Ziegler, A.-G., Heninger, A., Dahl, S., Klemroth, D., Kühn, A., Eugster, A., Lindner, M., Catani, A.-K., Eugster, A., Lindner, A., Catani, M., Heninger, A.-K., Dahl, A., Klemroth, S., & K€ Uhn, D. (2015). T Cells + GAD65 Autoantigen-Specific Human CD4 High Diversity in the TCR Repertoire of High Diversity in the TCR Repertoire of GAD65 Autoantigen-Specific Human CD4 + T Cells. J Immunol Material SupplementaryDCSupplemental.Html The Journal of Immunology The Journal of Immunology, 1(194), 0–0. http://www.jimmunol.org/content/early/2015/02/13/jimmun%5Cnhttp://www.jimmunol.org/

Zeigerer, A., Bogorad, R. L., Sharma, K., Gilleron, J., Seifert, S., Sales, S., Berndt, N., Bulik, S., Marsico, G., D’Souza, R. C. J., Lakshmanaperumal, N., Meganathan, K., Natarajan, K., Sachinidis, A., Dahl, A., Holzhütter, H. G., Shevchenko, A., Mann, M., Koteliansky, V., & Zerial, M. (2015). Regulation of Liver Metabolism by the Endosomal GTPase Rab5. Cell Reports, 11(6), 884–892. https://doi.org/10.1016/j.celrep.2015.04.018

Florio, M., Albert, M., Taverna, E., Namba, T., Brandl, H., Lewitus, E., Haffner, C., Sykes, A., Wong, F. K., Peters, J., Guhr, E., Klemroth, S., Prufer, K., Kelso, J., Naumann, R., Nusslein, I., Dahl, A., Lachmann, R., Paabo, S., & Huttner, W. B. (2015). Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion. Science, 347(6229), 1465–1470. https://doi.org/10.1126/science.aaa1975

Kretschmer, S., Wolf, C., König, N., Staroske, W., Guck, J., Häusler, M., Luksch, H., Nguyen, L. A., Kim, B., Alexopoulou, D., Dahl, A., Rapp, A., Cardoso, M. C., Shevchenko, A., & Lee-Kirsch, M. A. (2015). SAMHD1 prevents autoimmunity by maintaining genome stability. Annals of the Rheumatic Diseases, 74(3), e17–e17. https://doi.org/10.1136/annrheumdis-2013-204845

Mende, N., Kuchen, E. E., Lesche, M., Grinenko, T., Kokkaliaris, K. D., Hanenberg, H., Lindemann, D., Dahl, A., Platz, A., Höfer, T., Calegari, F., & Waskow, C. (2015). CCND1-CDK4-mediated cell cycle progression provides a competitive advantage for human hematopoietic stem cells in vivo. The Journal of Experimental Medicine, 212(8), 1171–1183. https://doi.org/10.1084/jem.20150308

Aprea, J., Lesche, M., Massalini, S., Prenninger, S., Alexopoulou, D., Dahl, A., Hiller, M., & Calegari, F. (2015). Identification and expression patterns of novel long non-coding RNAs in neural progenitors of the developing mammalian cortex. Neurogenesis, 2(1), e995524. https://doi.org/10.1080/23262133.2014.995524

2014

Cornils, K., Thielecke, L., Hüser, S., Forgber, M., Thomaschewski, M., Kleist, N., Hussein, K., Riecken, K., Volz, T., Gerdes, S., Glauche, I., Dahl, A., Dandri, M., Roeder, I., & Fehse, B. (2014). Multiplexing clonality: Combining RGB marking and genetic barcoding. Nucleic Acids Research, 42(7). https://doi.org/10.1093/nar/gku081

Lesche M., Krankel A., Dahl A., Roesler J., & Rosen- Wolff A. (2014). Detection of low frequency variants of nlrp3 in german “mutation-negative” CAPS patients by massive parallel sequencing. Journal of Clinical Immunology, S273. http://europepmc.org/abstract/PMC/PMC4597473

Clément-Ziza, M., Marsellach, F. X., Codlin, S., Papadakis, M. A., Reinhardt, S., Rodríguez-López, M., Martin, S., Marguerat, S., Schmidt, A., Lee, E., Workman, C. T., Bähler, J., & Beyer, A. (2014). Natural genetic variation impacts expression levels of coding, non-coding, and antisense transcripts in fission yeast. Molecular Systems Biology, 10(11), 764. https://doi.org/10.15252/msb.20145123

Heyn, P., Kircher, M., Dahl, A., Kelso, J., Tomancak, P., Kalinka, A. T., & Neugebauer, K. M. (2014). The earliest transcribed zygotic genes are short, newly evolved, and different across species. Cell Reports, 6(2), 285–292. https://doi.org/10.1016/j.celrep.2013.12.030

Huttner, H. B., Bergmann, O., Salehpour, M., Rácz, A., Tatarishvili, J., Lindgren, E., Csonka, T., Csiba, L., Hortobágyi, T., Méhes, G., Englund, E., Solnestam, B. W., Zdunek, S., Scharenberg, C., Ström, L., Ståhl, P., Sigurgeirsson, B., Dahl, A., Schwab, S., … Frisén, J. (2014). The age and genomic integrity of neurons after cortical stroke in humans. Nature Neuroscience, 17(6), 801–803. https://doi.org/10.1038/nn.3706

Henderson, D., Ogilvie, L. A., Hoyle, N., Keilholz, U., Lange, B., & Lehrach, H. (2014). Personalized medicine approaches for colon cancer driven by genomics and systems biology: OncoTrack. In Biotechnology Journal (Vol. 9, Issue 9, pp. 1104–1114). https://doi.org/10.1002/biot.201400109

Grinenko, T., Arndt, K., Portz, M., Mende, N., Günther, M., Cosgun, K. N., Alexopoulou, D., Lakshmanaperumal, N., Henry, I., Dahl, A., & Waskow, C. (2014). Clonal expansion capacity defines two consecutive developmental stages of long-term hematopoietic stem cells. The Journal of Experimental Medicine, 211(2), 209–215. https://doi.org/10.1084/jem.20131115

Vogt, I., Richter, K., Dahl, A., Hanke, M.-V., Flachowsky, H., & Peil, A. (2014). Differential transcriptome analysis of Malus x robusta 5 after inoculation with the virulent Erwinia amylovora avrRpt2<inf>EA</inf>deletion strain ZYRKD3-1 and the non-virulent wild type strain Ea1189. In Acta Horticulturae (Vol. 1056).

2013

Thieme, S., Gyárfás, T., Richter, C., Özhan, G., Fu, J., Alexopoulou, D., Muders, M. H., Michalk, I., Jakob, C., Dahl, A., Klink, B., Bandoła, J., Bachmann, M., Schröck, E., Buchholz, F., Francis Stewart, A., Weidinger, G., Anastassiadis, K., & Brenner, S. (2013). The histone demethylase UTX regulates stem cell migration and hematopoiesis. Blood, 121(13), 2462–2473. https://doi.org/10.1182/blood-2012-08-452003

Liu, S.-Y., Selck, C., Friedrich, B., Lutz, R., Vila-Farré, M., Dahl, A., Brandl, H., Lakshmanaperumal, N., Henry, I., & Rink, J. C. (2013). Reactivating head regrowth in a regeneration-deficient planarian species. Nature, 500(7460), 81–84. https://doi.org/10.1038/nature12414

Behrendt, R., Schumann, T., Gerbaulet, A., Nguyen, L. A., Schubert, N., Alexopoulou, D., Berka, U., Lienenklaus, S., Peschke, K., Gibbert, K., Wittmann, S., Lindemann, D., Weiss, S., Dahl, A., Naumann, R., Dittmer, U., Kim, B., Mueller, W., Gramberg, T., & Roers, A. (2013). Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response. Cell Reports, 4(4), 689–696. https://doi.org/10.1016/j.celrep.2013.07.037

Lesche, M., Dahl, A., Kränkel, A., Roesler, J., & Rösen-Wolff, A. (2013). PW02-026 – Low frequency variants of NLRP3 in CAPS patients. Pediatric Rheumatology, 11(Suppl 1), A167. https://doi.org/10.1186/1546-0096-11-S1-A167

Aprea, J., Prenninger, S., Dori, M., Ghosh, T., Monasor, L. S., Wessendorf, E., Zocher, S., Massalini, S., Alexopoulou, D., Lesche, M., Dahl, A., Groszer, M., Hiller, M., & Calegari, F. (2013). Transcriptome sequencing during mouse brain development identifies long non-coding RNAs functionally involved in neurogenic commitment. The EMBO Journal, 32(24), 3145–3160. https://doi.org/10.1038/emboj.2013.245

2012

Haupt, A., Joberty, G., Bantscheff, M., Fröhlich, H., Stehr, H., Schweiger, M. R., Fischer, A., Kerick, M., Boerno, S. T., Dahl, A., Lappe, M., Lehrach, H., Gonzalez, C., Drewes, G., & Lange, B. M. (2012). Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics. BMC Cancer, 12(1), 38. https://doi.org/10.1186/1471-2407-12-38

Börno, S. T., Fischer, A., Kerick, M., Fälth, M., Laible, M., Brase, J. C., Kuner, R., Dahl, A., Grimm, C., Sayanjali, B., Isau, M., Röhr, C., Wunderlich, A., Timmermann, B., Claus, R., Plass, C., Graefen, M., Simon, R., Demichelis, F., … Schweiger, M. R. (2012). Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation. Cancer Discovery, 2(11), 1024–1035. https://doi.org/10.1158/2159-8290.CD-12-0041

Clarke, L., Zheng-Bradley, X., Smith, R., Kulesha, E., Xiao, C., Toneva, I., Vaughan, B., Preuss, D., Leinonen, R., Shumway, M., Sherry, S., & Flicek, P. (2012). The 1000 Genomes Project: data management and community access. Nature Methods, 9(5), 459–462. https://doi.org/10.1038/nmeth.1974

Bormann, F., Dahl, A., & Sers, C. (2012). MsLDR-creator: A web service to design msLDR assays. Molecular Genetics and Genomics, 287(3), 273–274. https://doi.org/10.1007/s00438-012-0677-9

2011

Mills, R. E., Walter, K., Stewart, C., Handsaker, R. E., Chen, K., Alkan, C., Abyzov, A., Yoon, S. C., Ye, K., Cheetham, R. K., Chinwalla, A., Conrad, D. F., Fu, Y., Grubert, F., Hajirasouliha, I., Hormozdiari, F., Iakoucheva, L. M., Iqbal, Z., Kang, S., … Korbel, J. O. (2011). Mapping copy number variation by population-scale genome sequencing. Nature, 470(7332), 59–65. https://doi.org/10.1038/nature09708

Danecek, P., Auton, A., Abecasis, G., Albers, C. A., Banks, E., DePristo, M. A., Handsaker, R. E., Lunter, G., Marth, G. T., Sherry, S. T., McVean, G., & Durbin, R. (2011). The variant call format and VCFtools. Bioinformatics, 27(15), 2156–2158. https://doi.org/10.1093/bioinformatics/btr330

Marth, G. T., Yu, F., Indap, A. R., Garimella, K., Gravel, S., Leong, W., Tyler-Smith, C., Bainbridge, M., Blackwell, T., Zheng-Bradley, X., Chen, Y., Challis, D., Clarke, L., Ball, E. V, Cibulskis, K., Cooper, D. N., Fulton, B., Hartl, C., Koboldt, D., … Gibbs, R. (2011). The functional spectrum of low-frequency coding variation. Genome Biology, 12(9), R84. https://doi.org/10.1186/gb-2011-12-9-r84

von Keyserling, H., Bergmann, T., Schuetz, M., Schiller, U., Stanke, J., Hoffmann, C., Schneider, A., Lehrach, H., Dahl, A., & Kaufmann, A. M. (2011). Analysis of 4 single-nucleotide polymorphisms in relation to cervical dysplasia and cancer development using a high-throughput ligation-detection reaction procedure. Int J Gynecol Cancer, 21(9), 1664–1671. https://doi.org/10.1097/IGC.0b013e31822b6299

Bormann, F., Sers, C., Seliger, B., Handke, D., Bergmann, T., Seibt, S., Lehrach, H., & Dahl, A. (2011). Methylation-specific ligation detection reaction (msLDR): A new approach for multiplex evaluation of methylation patterns. Molecular Genetics and Genomics, 286(3–4), 279–291. https://doi.org/10.1007/s00438-011-0645-9

Conrad, D. F., Keebler, J. E. M., DePristo, M. A., Lindsay, S. J., Zhang, Y., Casals, F., Idaghdour, Y., Hartl, C. L., Torroja, C., Garimella, K. V, Zilversmit, M., Cartwright, R., Rouleau, G. A., Daly, M., Stone, E. A., Hurles, M. E., & Awadalla, P. (2011). Variation in genome-wide mutation rates within and between human families. Nature Genetics, 43(7), 712–714. https://doi.org/10.1038/ng.862

Gravel, S., Henn, B. M., Gutenkunst, R. N., Indap, A. R., Marth, G. T., Clark, A. G., Yu, F., Gibbs, R. A., Bustamante, C. D., Altshuler, D. L., Durbin, R. M., Abecasis, G. R., Bentley, D. R., Chakravarti, A., Clark, A. G., Collins, F. S., De La Vega, F. M., Donnelly, P., Egholm, M., … McVean, G. A. (2011). Demographic history and rare allele sharing among human populations. Proceedings of the National Academy of Sciences, 108(29), 11983–11988. https://doi.org/10.1073/pnas.1019276108

2010

Sudmant, P. H., Kitzman, J. O., Antonacci, F., Alkan, C., Malig, M., Tsalenko, A., Sampas, N., Bruhn, L., Shendure, J., & Eichler, E. E. (2010). Diversity of Human Copy Number Variation and Multicopy Genes. Science, 330(6004), 641–646. https://doi.org/10.1126/science.1197005

Dahl, A., Mertes, F., Timmermann, B., & Lehrach, H. (2010). The application of massively parallel sequencing technologies in diagnostics. F1000 Biology Reports, 2(August), 59. https://doi.org/10.3410/B2-59

Scholz, A.-K., Klebl, B. M., Morkel, M., Lehrach, H., Dahl, A., & Lange, B. M. H. (2010). A flexible multiwell format for immunofluorescence screening microscopy of small-molecule inhibitors. Assay and Drug Development Technologies, 8(5), 571–580. https://doi.org/10.1089/adt.2009.0260

Durbin, R. M., Altshuler, D. L., Durbin, R. M., Abecasis, G. R., Bentley, D. R., Chakravarti, A., Clark, A. G., Collins, F. S., De La Vega, F. M., Donnelly, P., Egholm, M., Flicek, P., Gabriel, S. B., Gibbs, R. A., Knoppers, B. M., Lander, E. S., Lehrach, H., Mardis, E. R., McVean, G. A., … McVean, G. A. (2010). A map of human genome variation from population-scale sequencing. Nature, 467(7319), 1061–1073. https://doi.org/10.1038/nature09534

McMeekin, T. A., Hill, C., Wagner, M., Dahl, A., & Ross, T. (2010). Ecophysiology of food-borne pathogens: Essential knowledge to improve food safety. International Journal of Food Microbiology, 139(SUPPL. 1). https://doi.org/10.1016/j.ijfoodmicro.2010.01.041

Mertes, F., Biens, K., Lehrach, H., Wagner, M., & Dahl, A. (2010). High-throughput Universal Probe Salmonella Serotyping (UPSS) by nanoPCR. Journal of Microbiological Methods, 83(2), 217–223. https://doi.org/10.1016/j.mimet.2010.09.005

Krawitz, P. M., Schweiger, M. R., Rödelsperger, C., Marcelis, C., Kölsch, U., Meisel, C., Stephani, F., Kinoshita, T., Murakami, Y., Bauer, S., Isau, M., Fischer, A., Dahl, A., Kerick, M., Hecht, J., Köhler, S., Jäger, M., Grünhagen, J., de Condor, B. J., … Robinson, P. N. (2010). Identity-by-descent filtering of exome sequence data identifies PIGV mutations in hyperphosphatasia mental retardation syndrome. Nature Genetics, 42(10), 827–829. https://doi.org/10.1038/ng.653